Molecular and cellular endocrinology was established in 1974 to meet the demand for integrated publication on all aspects related to the genetic and biochemical effects, synthesis and secretions of extracellular signals hormones, neurotransmitters, etc. Jci impact of estrogens in males and androgens in females. Journal of clinical endocrinology and metabolism print. The efficacy of thyrotropin suppression therapy in treatment. The extent of ntis is associated with prognosis, but no. Endocrinology, diabetes, and metabolism certification examination. Frontiers the love hormone oxytocin regulates the loss. Thieme ejournals experimental and clinical endocrinology. Thyrotropin suppression and disease progression in patients with differentiated thyroid cancer. Global consensus recommendations on prevention and management.
Subcutaneous adipose tissue releases interleukin6, but not tumor necrosis factor alpha, in vivo. Growth hormone excess that occurs before fusion of the epiphyseal growth plates in a child or adolescent is called pituitary gigantism. If you have the appropriate software installed, you can download article citation data to the citation manager of your choice. The endocrinology and metabolism is the official journal of the korean endocrine society. Hypothyroidism is a common condition of thyroid hormone deficiency, which is readily diagnosed and managed but potentially fatal in severe cases if untreated.
Over the past four decades, the number of children and adolescents with obesity has risen. Current status of endocrinology fellowship program and practicing clinicians. In this article, we discuss recent studies that have investigated the effects of exercise training on mitochondrial function, the beiging of wat. We investigated the impact of vitamin d repletion in asymptomatic patients with normocalcaemic and hypercalcaemic primary hyperparathyroidism.
The american journal of physiologyendocrinology and metabolism publishes original, mechanistic studies on the physiology of endocrine and metabolic systems. Nerve growth factor ngf regulates many aspects of neuronal biology by retrogradely propagating signals along axons to the targets of those axons. Impact of obesity on the health of women in midlife. Management should be straightforward but appears not to be the case. Leanne redman, ms, phd lpfa endowed fellowship professor.
Global consensus recommendations on prevention and management of nutritional rickets. High levels of testosterone affect women and men differently. Despite the increased number of published cases, the pathogenesis of hypophysitis is poorly. Due to the increased use of opioids, it has become increasingly important to identify the prevalence and impact of opioid exposurerelated endocrine deficits. Longterm observation of 87 girls with idiopathic central precocious puberty treated with gonadotropinreleasing hormone analogs. Volume 100, issue 1, 1 january 2015 journals oxford academic. Patients in the intensive care unit icu typically present with decreased concentrations of plasma triiodothyronine, low thyroxine, and normal range or slightly decreased concentration of thyroidstimulating hormone. Elevated microparticle tissue factor activity is associated with carotid artery plaque in hivinfected women j acquir immune defic syndr. Rapid deterioration of insulin secretion in obese adolescents preceding the onset of type 2 diabetes.
Having a high level of circulating testosterone actually impacts the health of men and women in notably different ways, 1 according to evidence gathered by a team of international researchers. Title changed to archives of endocrinology and metabolism since 2015. The official title of the journal is endocrinology and metabolism and the abbreviated title is endocrinol metab enm. Simply select your manager software from the list below and click on download. Enter journal title, issn or abbr in this box to search. Adjuvant and definitive radiotherapy for adrenocortical carcinoma. An increasing number of epidemiological studies show an association between short sleep duration, sleep disturbances, and circadian desynchronisation of sleep with adverse metabolic traits, in particular obesity and type 2 diabetes.
Skeletal muscle dysfunction occurs during the aging process, involving impaired glucose uptake 10, 41, 46, increased intramuscular lipid, and reduced mitochondria oxidative capacity 21, 46, and is speculated to contribute to agerelated whole body insulin resistance. Thieme ejournals hormone and metabolic research abstract. The journal of clinical endocrinology and metabolism rg. Diabetes complications and osteoporotic fractures are two of the most important causes of morbidity and mortality in older patients and share many features including genetic susceptibility, molecular mechanisms, and environmental factors.
This article focuses on recent progress in understanding the genetics of lipodystrophy syndromes, the pathophysiology of severe metabolic abnormalities caused by these syndromes, and causes of severe morbidity and a possible signal of increased mortality associated with lipodystrophy. Volume 104 issue 7 the journal of clinical endocrinology. Editorinchief, associate editors, and editorial board. Impact of monitoring plasma 1,1dichlorodiphenildichloroethane o,pddd levels on the treatment of patients with adrenocortical carcinoma. The microbiota has been identified as an important factor in health and in a variety of diseases. Management of hyperglycemia in hospitalized patients in non. Leucine and insulin activate p70 s6 kinase through different. Elder da, hornung ln, herbers pm, prigeon r, woo jg, dalessio da. January december 2019 the editors and the authors of the papers submitted. J clin endocrinol metab, volume 100, issue 1, 1 january 2015. Endocrinology and metabolism impact factor abbreviation. Moro c, klimcakova e, lolmede k, berlan m, lafontan m, stich v, bouloumie a, galitzky j, arner p, langin d.
Obesity is a risk factor for menopausal symptoms and depression. Study of 32 children to evaluate longterm cognitive effects of gc replacement therapy and the impact of early diagnosis in children with cah shows that children. The current impact factor is 1,141 5 year impact factor 1,070 czech impact journals all journals categories. Reexamination of testosterone, dihydrotestosterone, estradiol and estrone levels across the menstrual cycle and in postmenopausal women measured by liquid chromatographytandem mass spectrometry. An altered microbiota composition increases the prevalence of hashimotos thyroiditis ht and graves disease gd. Indian journal of endocrinology and metabolism impact factor. In adults the excess growth hormone secretion is usually caused by a benign.
Jun 11, 2015 praderwilli syndrome pws is a multisystemic complex genetic disorder caused by lack of expression of genes on the paternally inherited chromosome 15q11. While you are likely to consider testosterone as a mans hormone, this naturally occurring sex hormone is actually produced in the bodies of. Ross and oliver blankenstein on being awarded the society for endocrinology 2019 journal award for their paper absorption and tolerability of taste. Changes in basal and insulin and amino acid response of whole body and skeletal muscle proteins in obese men. Whitaker, susanna wiegand, heiko krude, john porter, madhu davies, dena digweed, bernard voet, richard j. Efficacy of bcell targeted therapy with rituximab in patients with active moderatesevere graves orbitopathy. Moreover, several lines of evidence have largely demonstrated that ot also participates in the regulation of energy metabolism. Feeding influences adipose tissue responses to exercise in. Only in the polish version of the website it is possible to download the fulltext of the documents. Comparison of the efficacy and safety of insulin detemir administered once daily according to two titration algorithms 303 and 2468 in patients with type 2 diabetes mellitus. American journal of physiologyendocrinology and metabolism.
Trasande l, zoeller rt, hass u, kortenkamp a, grandjean p, myers jp, digangi j, bellanger m, hauser r, legler j, skakkebaek ne, heindel jj. May 18, 2015 the involvement of oxytocin ot in bone metabolism is an interesting area of research that recently achieved remarkable results. An endocrine society clinical practice guideline guillermo e. We advise that only trained mental health professionals mhps who meet the following criteria should diagnose gender dysphoria gd. Impact of obesity on the health of women in midlife lumsden. Impact of type of preadmission sulfonylureas on mortality and cardiovascular outcomes in diabetic patients with acute myocardial infarction. Molecular and cellular endocrinology journal elsevier.
Jci metabolically normal obese people are protected from. Globally, it is expected to afflict around 500 million people by 2030. Publishes endocrine clinical research and practice information including new developments enhancing our understanding of pathophysiology, diagnosis, and treatment of endocrine and metabolic disorders. In press, journal preproof, available online 2 april 2020. Journal of endocrinology impact factor, if, number of article, detailed information. The effect of betablockers on bone metabolism as potential drugs under investigation for osteoporosis and fracture healing. Yang sj, hwang sy, choi hy, yoo hj, seo ja, kim sg, et al. Kapitza c, nosek l, schneider w, teichert l, nowotny i. Thyroid cancer incidence in india between 2006 and 2014 and impact of. Vitamin d deficiency is increasingly recognized in patients with primary hyperparathyroidism but some clinicians are reluctant to replace vitamin d due to concerns with aggravating hypercalcaemia.
How this occurs when axons contain a plethora of proteins that can silence those. A consensus statement on acromegaly therapeutic outcomes. Nov 27, 2015 the currently available somatostatin receptor ligands srls and growth hormone gh antagonists are used to control levels of gh and insulinlike growth factor 1 igf1 in patients with acromegaly. Impact of type of preadmission sulfonylureas on mortality. Childhood obesity and the associated rise in cardiometabolic. Minimal impact of excess iodate intake on thyroid hormones and selenium status in older new zealanders. Why has the impact factor if of the journal been stuck at the same level for years, whereas ifs for. A reverse j shaped association between serum 25hydroxyvitamin d and cardiovascular disease mortality. Microbiota and thyroid interaction in health and disease.
Acromegaly is a clinical disorder of adults characterised by changes in the face and extremities caused by excess growth hormone secretion. Journal of endocrinology impact factor if 201920182017. Mar 16, 2020 childhood obesity is one of the most serious global publichealth challenges of the twentyfirst century. A retrospective cohort analysis of the efficacy of adjuvant radiotherapy after primary surgical resection in patients with adrenocortical carcinoma.
Diabetes, and particularly type 2 diabetes t2d, is increasing at an epidemic scale worldwide. Phenotypic and genetic characteristics of lipodystrophy. International journal of obesity and related metabolic disorders. The spectrum of hypophysitis has expanded in recent years with the addition of two histologic subtypes and recognition as a complication of treatment with immune checkpoint inhibitors. The metabolic burden of sleep loss the lancet diabetes. Obese human chorionic gonadotropins and insulin resistancemodeled cells and compound 21 as an inhibitor of glycogen synthase kinase 3. Endocrinology and metabolism impact factor journal data. International journal of clinical endocrinology and metabolism. Obesity inhibits fsh receptor fshr expression and estradiol production. An updated classification scheme is also presented. Pasquino, am, pucarelli, i, accardo, f, demiraj, v, segni, m, di nardo, r.
In parallel with the increasing prevalence of obesity and type 2 diabetes, sleep loss has become common in modern societies. New jcem format the journal of clinical endocrinology. Endocrine treatment of genderdysphoricgenderincongruent. Regular physical activity and exercise training have long been known to cause adaptations to white adipose tissue wat, including decreases in cell size and lipid content and increases in mitochondrial proteins. Conditions of gh deficiency and genetic resistance impact cortical and trabecular bone deleteriously with reduced estimates of bone strength.
The current impact factor is 1,141 5 year impact factor 1,070. However, 1015% of patients established on levothyroxine. Hypothyroidism is common throughout the world and readily diagnosed with thyroid function tests. Serum selenoprotein p levels in patients with type 2 diabetes and prediabetes. Hence, it has recently been determined that the posterior pituitary hormone ot directly regulates bone mass. Growth hormone gh and insulin like growth factor i igf i are key bone trophic hormones, whose rising levels during puberty are critical for pubertal bone accrual. Weight gain in pregnancy and application of the 2009 iom guidelines.
Journal of clinical endocrinology and metabolism impact factor, if, number of article, detailed information and journal factor. Prevalence of obesity and metabolic syndrome in children with type 1 diabetes. A pediatricians guide to central precocious puberty gad b. Graves orbitopathy has a negative impact on a patients quality of life.
Iodine excess as an environmental risk factor for autoimmune thyroid disease. The journal of clinical endocrinology and metabolism rg journal. Hypophysitis is the acute or chronic inflammation of the pituitary gland. Journal of clinical endocrinology and metabolism impact. Ernie hood is a contract writer with the niehs office of communications and public liaison. Microbes influence thyroid hormone levels by regulating iodine uptake, degradation, and enterohepatic cycling. Effect of protein overfeeding on energy expenditure measured in a metabolic chamber. The journal is published six times a year, with one issue every two months. New insights into the pathogenesis and nonsurgical. The epidemic of t2d is attributed to our changed lifestyle, with less physical activity and fastfood. The journal of clinical endocrinology and metabolism. Endocrine society draft clinical practice guideline on gender dysphoria gender incongruence publication expected september, 2017. An abundant supply of amino acids enhances the metabolic effect of exercise on muscle protein. Journal rankings on endocrinology, diabetes and metabolism.
Singledose euglycemic clamp study demonstrating pharmacokinetic and pharmacodynamic similarity between sar341402 insulin aspart and us and euapproved versions of insulin aspart in subjects with type 1 diabetes. In addition, there is a pronounced influence of minerals on. Thyroid hormone replacement with levothyroxine monotherapy is the standard treatment which is effective in the majority of cases. Here, we tested the hypothesis that people defined by ihtg content and insulin sensitivity as metabolically normal obese mno, but not those defined as metabolically abnormal obese mao, are protected from the adverse metabolic effects of weight gain. Management of hyperglycemia in hospitalized patients in noncritical care setting. The 11th acromegaly consensus conference in april 2017 was convened to update recommendations on therapeutic outcomes for patients with acromegaly. A comparative assessment based on criteria established by the international diabetes federation, world health organisation and national cholesterol education program. Type 2 diabetes mellitus t2dm compromises bone microarchitecture by inducing abnormal bone cell function and. The definition of hypothyroidism is based on statistical reference ranges of the relevant biochemical parameters and is increasingly a matter of debate.
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